The Science of Re-Storation
Rigorous science begins with a refusal to simplify. Every rare compound is selected for its biological role, every result clinically verified. Not the appearance of healthier skin. The biology of it.
the origin
Dr. Jennifer Biglow
A renowned dermatologist, Dr. Jennifer Biglow developed the original Re-Storation® formula inside her clinical practice in 1998, not as a commercial product, but as the answer to a clinical question her patients kept asking.
Board-certified and clinically published, she was guided by a single conviction: that skin deserves a formula built around its own intelligence. Her original formulation became the starting point for everything Z. Bigatti has built since.
Clinical Intelligence
Re-Storation® was developed through direct clinical observation, tracking the skin's cellular response to active compounds in real time within a dermatology practice. Every formulation decision was made at the level of epidermal biology: barrier function, cellular turnover, and the biochemical signals that drive genuine renewal.
next chapter
The Standard Continues.
Dr. Jennifer Biglow established the founding clinical principles of Re-Storation® in 1998. Today, Rachel Stevens, PA-C, a certified physician assistant and dermatology specialist, serves as Z. Bigatti's clinical advisor. The standard is unchanged. The science continues.
skin Intelligence
Five Biological Skin Dimensions. One Treatment.
The Re-Storation® formula does not address one concern and leave the rest to chance. It works across five biological dimensions that determine how skin ages, renews, and protects itself. Simultaneously, in a single application.
1. Surface renewal
Botanical enzymes deliver a clinically verified 41% increase in cell renewal rate.
2. Barrier restoration
Phytosteryl Macadamia holds 300× its weight in water. 36% recovery of moisture retention.
3. Collagen synthesis
Peptide complex signals skin to produce collagen, elastin, and hyaluronic acid simultaneously.
4. Cellular communication
L-Arginine and Hyaluronic Acid at 5% guiding skin toward its own most vital state.
5. Antioxidant protection
Five antioxidant sources, each targeting a different mechanism of environmental damage.
bioidentical
Every Ingredient Earns Its Place.
We source from the rarest coordinates of the natural world and the most advanced biomedical laboratories. Each compound is selected for its documented mechanism of action, its bioavailability, and its compatibility within the larger formula. Nothing else qualifies.
Snake Venom Peptides
Inhibits the micro-muscle contractions that deepen expression lines over time. Nature's most precise alternative to clinical intervention, applied through the skin's own surface.
Enzyme Renewal Complex
Papain, Bromelain & Sutilains, clinically studied 41% increase in cell renewal rate.
Multi-Peptide Complex
Signals fibroblast cells to produce collagen and elastin at a higher rate. The molecular language the skin already speaks, amplified.
since 1998
Science Was Always There
Every principle established in 1998 remains intact. What has changed is the depth of the science, the purity of the ingredients, and the precision of the formulation. Not a reinvention. The refinement.
1998
Developed in a Minneapolis dermatology clinic, built around cellular intelligence the industry had yet to explore.
Early 2000's
Saks Fifth Avenue. The Oscars gift selection. Re-Storation® had been passed between women quietly.
2003-2005
Cannes Film Festival, Grammy Awards gift basket, 76th Academy Awards gift basket, MTV VMAs. Sports Illustrated. Sundance Film Festival.
2006-2007
Elle, Allure, Vogue, Harper's Bazaar, Lucky, People, Us Weekly, Forbes, ABC News Hot List. No paid placement. Ever.
2026
Cleaner. Deeper. The most botanically enriched expression of the founding formula to date.